This is where I work through nanomedicine in writing. Some posts explain a concept as clearly as I can manage; some are notes on papers I’ve read; some are reflections on what I’m learning and where I keep getting stuck. The aim is clarity, not authority; if a sentence sounds impressive but means nothing, it shouldn’t be here.
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A Blood Test That Can Find Cancer Before You Feel It
There’s something quietly remarkable about the idea that cancer might leave traces in your blood long before you notice anything is wrong. Not obvious signs — just fragments. Tiny pieces of DNA shed by…
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The AI Scientist has not caught up to the hype
There’s a comforting story that’s going around about AI and medicine: feed a model enough data, and out pops the next miracle drug. It’s a tidy narrative. It’s also not quite true, and the…
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Teaching the Immune System to Fight Childhood Cancer — With mRNA and Peptides
There are few things in oncology more sobering than paediatric cancer statistics. Neuroblastoma — a tumour that develops in immature nerve cells and typically affects children under five — accounts for around 15% of…
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MIT’s Nanotube Sensor That Finds Bladder Cancer Before You Can See It
Bladder cancer has an unfair reputation for being survivable — which it often is, when caught early. The less-discussed part is what “early” actually looks like in practice: roughly 85,000 people are diagnosed in…
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A Baby, a Base Editor, and Six Months to Save a Life
There is a version of this story that ends badly. It almost did. KJ Muldoon was born with severe carbamoyl phosphate synthetase 1 deficiency — a mouthful of a diagnosis that essentially means his…
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Diagnosing Brain Tumours While the Patient Is Still in Surgery?
There’s a particular kind of pressure in a neurosurgical theatre. A surgeon has just removed a small piece of brain tissue — a biopsy, perhaps only a millimetre or two across — and what…
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Paula Hammond Is Teaching Nanoparticles to Multitask — And It Might Change How We Treat Cancer
There is a particular frustration in oncology that does not get discussed enough outside of research circles: cancer adapts. You give a patient a drug. It works — sometimes brilliantly, sometimes briefly — and…
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Tiny Balls, Big Problems: How SNAs Are Sneaking Past the Brain’s Defences
There is a reason glioblastoma has gone decades without a new approved drug. It is not that scientists haven’t tried. It is that the brain, in its infinite wisdom, has constructed a wall so…
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When Your Skin Has a Better Idea Than Your Surgeon
There’s a compound in your skin that protects you from UV radiation, tints peacock feathers iridescent blue without a single drop of blue pigment, and is found in deep-sea fish that have never once…